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NDB ID: 6BSJ    PDB ID: 6BSJ 


Title:

STRUCTURE OF HIV-1 RT COMPLEXED WITH AN RNA/DNA HYBRID SEQUENCE NON-PREFERRED FOR RNA HYDROLYSIS

Molecular Description:

REVERSE TRANSCRIPTASE P66 SUBUNIT
REVERSE TRANSCRIPTASE P51 SUBUNIT/DNA Complex

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Tian, L., Kim, M.S., Li, H., Wang, J., Yang, W.
Structure of HIV-1 reverse transcriptase cleaving RNA in an RNA/DNA hybrid. 
Proc. Natl. Acad. Sci. U.S.A., 115, pp. 507 - 512, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 163.24   b = 163.24   c = 129.4 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2028 for 44853 reflections in the resolution range 41.199 to 2.89 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)