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NDB ID: 6B0Q    PDB ID: 6B0Q 


Title:

ZINC FINGER DOMAIN OF WT1(-KTS FORM) WITH 13+1MER OLIGONUCLEOTIDE WITH 3' TRIPLET TGT

Molecular Description:

Wilms tumor protein/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Wang, D., Horton, J.R., Zheng, Y., Blumenthal, R.M., Zhang, X., Cheng, X.
Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites. 
Nucleic Acids Res., , pp. - , 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 63

Cell Constants:

a = 161.664   b = 161.664   c = 42.172 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2262 for 30219 reflections in the resolution range 38.83 to 2.794 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)