A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 17-Apr-2018 number of released structures: 9452
Search for released structures

NDB ID: 6B0O    PDB ID: 6B0O 


Title:

ZINC FINGER DOMAIN OF WT1(-KTS FORM) WITH 12+1MER OLIGONUCLEOTIDE WITH 3' TRIPLET TGT

Molecular Description:

Wilms tumor protein/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Wang, D., Horton, J.R., Zheng, Y., Blumenthal, R.M., Zhang, X., Cheng, X.
Role for first zinc finger of WT1 in DNA sequence specificity: Denys-Drash syndrome-associated WT1 mutant in ZF1 enhances affinity for a subset of WT1 binding sites. 
Nucleic Acids Res., , pp. - , 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 36.927   b = 42.657   c = 71.821 (Ångstroms)

α = 88.28   β = 77.71   γ = 85.81 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1933 for 118578 reflections in the resolution range 29.588 to 1.552 Ångstroms with Fobs >  1.96 sigma(Fobs) and with I >  0.0 sigma(I)