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NDB ID: 5X07    PDB ID: 5X07 


Title:

CRYSTAL STRUCTURE OF FOXA2 DNA BINDING DOMAIN BOUND TO A FULL CONSENSUS DNA SITE

Molecular Description:

Hepatocyte nuclear factor 3-beta/DNA Complex

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Li, J., Machado, A.C.D., Guo, M., Sagendorf, J.M., Zhou, Z., Jiang, L., Chen, X., Wu, D., Qu, L., Chen, Z., Chen, L., Rohs, R., Chen, Y.
Structure of the Forkhead Domain of FOXA2 Bound to a Complete DNA Consensus Site 
Biochemistry, 56, pp. 3745 - 3753, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 195.126   b = 71.932   c = 72.155 (Ångstroms)

α = 90.0   β = 103.14   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2431 for 23493 reflections in the resolution range 33.637 to 2.796 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)