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NDB ID: 5W6V    PDB ID: 5W6V 


Title:

THE STRUCTURE OF HUMAN ARGONAUTE-1 IN COMPLEX WITH THE HOOK MOTIF OF HUMAN GW182

Molecular Description:

Protein argonaute-1
Trinucleotide repeat-containing gene 6A protein/RNA Complex

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Elkayam, E., Faehnle, C.R., Morales, M., Sun, J., Li, H., Joshua-Tor, L.
Multivalent Recruitment of Human Argonaute by GW182. 
Mol. Cell, 67, pp. 646 - 658.e3, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 93.75   b = 136.861   c = 86.054 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2022 for 27079 reflections in the resolution range 77.344 to 2.828 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)