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NDB ID: 5W2C    PDB ID: 5W2C 


Title:

STRUCTURE OF HUMAN DNA POLYMERASE KAPPA IN COMPLEX WITH LUCIDIN-DERIVED DNA ADDUCT AND INCOMING DAMPNPP

Molecular Description:

DNA polymerase kappa/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yockey, O., Jha, V., Ghodke, P.P., Xu, T., Xu, W., Ling, H., Pradeepkumar, P.I., Zhao, L.
Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase kappa. 
Chem. Res. Toxicol., , pp. - , 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 63.709   b = 128.923   c = 167.705 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.21217 for 47145 reflections in the resolution range 50.01 to 2.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)