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NDB ID: 5VZ7    PDB ID: 5VZ7 


Title:

PRE-CATALYTIC TERNARY COMPLEX OF HUMAN POLYMERASE MU (G433A) MUTANT WITH INCOMING NONHYDROLYZABLE UMPNPP

Molecular Description:

DNA-directed DNA/RNA polymerase mu/DNA Complex

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.
Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu. 
Nucleic Acids Res., 45, pp. 9138 - 9148, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 59.805   b = 68.825   c = 109.757 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.171 for 63709 reflections in the resolution range 40.435 to 1.551 Ångstroms with Fobs >  1.5 sigma(Fobs) and with I >  0.0 sigma(I)