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NDB ID: 5VH8    PDB ID: 5VH8 


Title:

STRUCTURE AND DYNAMICS OF RNA REPEAT EXPANSIONS THAT CAUSE HUNTINGTON'S DISEASE AND MYOTONIC DYSTROPHY TYPE 1

Molecular Description:

RNA (5'-R(*GP*AP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*C)-3')

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Chen, J.L., VanEtten, D.M., Fountain, M.A., Yildirim, I., Disney, M.D.
Structure and Dynamics of RNA Repeat Expansions That Cause Huntington's Disease and Myotonic Dystrophy Type 1. 
Biochemistry, 56, pp. 3463 - 3474, 2017.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Number of Models:

Number of Models: 20 Structures

Sample Details:

0.5 mM NA Adenosine, Cytidine,Guanosine, Uridine RNA (5'-R(*GP*AP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*C)-3'), 5.0 mM potassium phosphate, 0.25 mM EDTA, 100% D2O 100% D2O