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NDB ID: 5UEF    PDB ID: 5UEF 


Title:

RNA PRIMER-TEMPLATE COMPLEX WITH GUANOSINE DINUCLEOTIDE P(5')G(3')P(5')G LIGAND

Molecular Description:

RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3')
RNA (5'-R(P*GP*G)-3')

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Zhang, W., Tam, C.P., Walton, T., Fahrenbach, A.C., Birrane, G., Szostak, J.W.
Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex. 
Proc. Natl. Acad. Sci. U.S.A., 114, pp. 7659 - 7664, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 3 2 1

Cell Constants:

a = 43.628   b = 43.628   c = 84.051 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.24289 for 5391 reflections in the resolution range 50.0 to 2.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)