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NDB ID: 5UEE    PDB ID: 5UEE 


Title:

RNA PRIMER-TEMPLATE COMPLEX WITH GUANOSINE DINUCLEOTIDE LIGAND G(5')PPP(5')G

Molecular Description:

RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*GP*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3')

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Tam, C.P., Zhang, W., Walton, T., Fahrenbach, A., Birrane, G., Szostak, J.W.
Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex 
Proc.Natl.Acad.Sci.Usa, , pp. - , 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 3 2 1

Cell Constants:

a = 46.964   b = 46.964   c = 83.103 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.8.0135 program. The R value is 0.23406 for 8299 reflections in the resolution range 50.0 to 1.9 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)