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NDB ID: 5UA3    PDB ID: 5UA3 


Title:

CRYSTAL STRUCTURE OF A DNA G-QUADRUPLEX WITH A CYTOSINE BULGE

Molecular Description:

Human telomerase RNA component (TERC) DNA analogue
nucleotides 1-20

Structural Keywords:

QUADRUPLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Meier, M., Moya-Torres, A., Krahn, N.J., McDougall, M.D., Orriss, G.L., McRae, E.K.S., Booy, E.P., McEleney, K., Patel, T.R., McKenna, S.A., Stetefeld, J.
Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge. 
Nucleic Acids Res., 46, pp. 5319 - 5331, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 30.103   b = 33.1   c = 33.282 (Ångstroms)

α = 64.65   β = 78.64   γ = 81.78 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2288 for 8254 reflections in the resolution range 19.4935 to 1.8802 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)