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NDB ID: 5U9B    PDB ID: 5U9B 


Title:

SOLUTION STRUCTURE OF THE ZINC FINGERS 1 AND 2 OF MBNL1 IN COMPLEX WITH HUMAN CARDIAC TROPONIN T PRE-MRNA

Molecular Description:

Muscleblind-like protein 1/RNA Complex

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Park, S., Phukan, P.D., Zeeb, M., Martinez-Yamout, M.A., Dyson, H.J., Wright, P.E.
Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T. 
Biochemistry, 56, pp. 4154 - 4168, 2017.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Number of Models:

Number of Models: 20 Structures

Sample Details:

0.4 mM [U-98% 13C; U-98% 15N] Zinc fingers 1 and 2 of MBNL1, 0.4 mM unlabeled RNA (5'-R(P*GP*UP*CP*UP*CP*GP*CP*UP*UP*UP*UP*CP*CP*CP*C)-3'), 90% H2O/10% D2O 90% H2O/10% D2O