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NDB ID: 5U8G    PDB ID: 5U8G 


Title:

DNA POLYMERASE BETA CRYSTALLIZED IN PEG 400

Molecular Description:

DNA polymerase beta/DNA Complex

Structural Keywords:

B DOUBLE HELIX, NICKED

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Eckenroth, B.E., Towle-Weicksel, J.B., Nemec, A.A., Murphy, D.L., Sweasy, J.B., Doublie, S.
Remote Mutations Induce Functional Changes in Active Site Residues of Human DNA Polymerase beta. 
Biochemistry, 56, pp. 2363 - 2371, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 54.104   b = 78.659   c = 54.721 (Ångstroms)

α = 90.0   β = 104.25   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1839 for 45604 reflections in the resolution range 13.68 to 2.166 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)