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NDB ID: 5U01    PDB ID: 5U01 


Title:

COOPERATIVE DNA BINDING BY TWO RELA DIMERS

Molecular Description:

Transcription factor p65/DNA Complex

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Mulero, M.C., Huang, D.B., Nguyen, H.T., Wang, V., Li, Y., Biswas, T., Ghosh, G.
DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor kappa B are not correlated. 
J. Biol. Chem., , pp. - , 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 88.91   b = 117.8   c = 70.81 (Ångstroms)

α = 90.0   β = 91.2   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.221 for 43116 reflections in the resolution range 29.63 to 2.5 Ångstroms with Fobs >  1.0 sigma(Fobs) and with I >  0.0 sigma(I)