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NDB ID: 5TBW    PDB ID: 5TBW 


Title:

CRYSTAL STRUCTURE OF CHLOROLISSOCLIMIDE BOUND TO THE YEAST 80S RIBOSOME

Molecular Description:

Nucleic Acid Sequence:

Click to show/hide 4 nucleic acid sequences

Protein Sequence:

Click to show/hide 79 protein sequences

Primary Citation:

Konst, Z.A., Szklarski, A.R., Pellegrino, S., Michalak, S.E., Meyer, M., Zanette, C., Cencic, R., Nam, S., Voora, V.K., Horne, D.A., Pelletier, J., Mobley, D.L., Yusupova, G., Yusupov, M., Vanderwal, C.D.
Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides 
Nat.Chem., , pp. - , 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 304.8   b = 288.2   c = 437.68 (Ångstroms)

α = 90.0   β = 98.71   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1944 for 1484577 reflections in the resolution range 99.856 to 3.0 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)