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NDB ID: 5T4I    PDB ID: 5T4I 


Title:

A NOVEL DOMAIN IN HUMAN EXOG CONVERTS APOPTOTIC ENDONUCLEASE TO DNA-REPAIR ENZYME

Molecular Description:

Nuclease EXOG
mitochondrial/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Szymanski, M.R., Yu, W., Gmyrek, A.M., White, M.A., Molineux, I.J., Lee, J.C., Yin, Y.W.
A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease. 
Nat Commun, 8, pp. 14959 - 14959, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 73.508   b = 79.723   c = 138.87 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1928 for 32548 reflections in the resolution range 40.031 to 2.389 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)