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NDB ID: 5OMW    PDB ID: 5OMW 


Title:

MUTANT T252A OF E. COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND LEUCYL-ADENYLATE ANALOGUE IN THE AMINOACYLATION CONFORMATION

Molecular Description:

Leucine--tRNA ligase/RNA Complex

Structural Keywords:

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Dulic, M., Cvetesic, N., Zivkovic, I., Palencia, A., Cusack, S., Bertosa, B., Gruic-Sovulj, I.
Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. 
J. Mol. Biol., 430, pp. 1 - 16, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 158.25   b = 68.91   c = 228.33 (Ångstroms)

α = 90.0   β = 104.93   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.22092 for 69873 reflections in the resolution range 220.62 to 2.6 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)