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NDB ID: 5NRG    PDB ID: 5NRG 


Title:

THE CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT OF STAPHYLOCOCCUS AUREUS IN COMPLEX WITH RB02

Molecular Description:

50S ribosomal protein L2
50S ribosomal protein L3
50S ribosomal protein L4
50S ribosomal protein L5
50S ribosomal protein L6
50S ribosomal protein L13
50S ribosomal protein L14
50S ribosomal protein L15
50S ribosomal protein L16
50S ribosomal protein L17
50S ribosomal protein L18
50S ribosomal protein L19
50S ribosomal protein L20
50S ribosomal protein L21
50S ribosomal protein L22
50S ribosomal protein L23
50S ribosomal protein L24
50S ribosomal protein L25
50S ribosomal protein L27
50S ribosomal protein L28
50S ribosomal protein L29
50S ribosomal protein L30
50S ribosomal protein L32
50S ribosomal protein L34
50S ribosomal protein L35/RNA Complex

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 24 protein sequences

Primary Citation:

Matzov, D., Eyal, Z., Benhamou, R.I., Shalev-Benami, M., Halfon, Y., Krupkin, M., Zimmerman, E., Rozenberg, H., Bashan, A., Fridman, M., Yonath, A.
Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus. 
Nucleic Acids Res., 45, pp. 10284 - 10292, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 279.797   b = 279.797   c = 873.274 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.221 for 254546 reflections in the resolution range 49.369 to 3.442 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)