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NDB ID: 5MGA    PDB ID: 5MGA 


Title:

STRUCTURE OF THE CPF1 ENDONUCLEASE R-LOOP COMPLEX AFTER DNA CLEAVAGE

Molecular Description:

CRISPR-associated endonuclease Cpf1/RNA Complex

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Stella, S., Alcon, P., Montoya, G.
Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage. 
Nature, 546, pp. 559 - 563, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 85.223   b = 137.652   c = 320.513 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2428 for 35724 reflections in the resolution range 39.58 to 3.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)