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NDB ID: 5MEY    PDB ID: 5MEY 


Title:

CRYSTAL STRUCTURE OF SMAD4-MH1 BOUND TO THE GGCGC SITE.

Molecular Description:

Mothers against decapentaplegic homolog 4/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Martin-Malpartida, P., Batet, M., Kaczmarska, Z., Freier, R., Gomes, T., Aragon, E., Zou, Y., Wang, Q., Xi, Q., Ruiz, L., Vea, A., Marquez, J.A., Massague, J., Macias, M.J.
Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. 
Nat Commun, 8, pp. 2070 - 2070, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 64.17   b = 79.0   c = 90.1 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the BUSTER program. The R value is 0.223 for 14709 reflections in the resolution range 29.7 to 2.05 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)