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NDB ID: 5KEG    PDB ID: 5KEG 


Title:

CRYSTAL STRUCTURE OF APOBEC3A IN COMPLEX WITH A SINGLE-STRANDED DNA

Molecular Description:

DNA dC->dU-editing enzyme APOBEC-3A/DNA Complex

Structural Keywords:

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Kouno, T., Silvas, T.V., Hilbert, B.J., Shandilya, S.M.D., Bohn, M.F., Kelch, B.A., Royer, W.E., Somasundaran, M., Kurt Yilmaz, N., Matsuo, H., Schiffer, C.A.
Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity. 
Nat Commun, 8, pp. 15024 - 15024, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 2 2 2

Cell Constants:

a = 56.583   b = 72.666   c = 114.971 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the program. The R value is 0.0 for 12146 reflections in the resolution range 30.71 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)