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NDB ID: 5GTC    PDB ID: 5GTC 


Title:

CRYSTAL STRUCTURE OF COMPLEX BETWEEN DMAP-SH CONJUGATED WITH A KAPOSI'S SARCOMA HERPESVIRUS LANA PEPTIDE (5-15) AND NUCLEOSOME CORE PARTICLE

Molecular Description:

Histone H3.1
Histone H4
Histone H2A type 1-B/E
Histone H2B type 1-J
LANA peptide/DNA Complex

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 5 protein sequences

Primary Citation:

Amamoto, Y., Aoi, Y., Nagashima, N., Suto, H., Yoshidome, D., Arimura, Y., Osakabe, A., Kato, D., Kurumizaka, H., Kawashima, S.A., Yamatsugu, K., Kanai, M.
Synthetic Posttranslational Modifications: Chemical Catalyst-Driven Regioselective Histone Acylation of Native Chromatin. 
J. Am. Chem. Soc., 139, pp. 7568 - 7576, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 107.225   b = 109.017   c = 176.194 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.214 for 56588 reflections in the resolution range 48.59 to 2.7 Ångstroms with Fobs >  1.44 sigma(Fobs) and with I >  0.0 sigma(I)