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NDB ID: 5GKR    PDB ID: 5GKR 


Title:

CRYSTAL STRUCTURE OF SLE PATIENT-DERIVED ANTI-DNA ANTIBODY IN COMPLEX WITH OLIGONUCLEOTIDE

Molecular Description:

IgG2
Fab (heavy chain)
lambda
Fab (light chain)/DNA Complex

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Sakakibara, S., Arimori, T., Yamashita, K., Jinzai, H., Motooka, D., Nakamura, S., Li, S., Takeda, K., Yasui, T., Narazaki, M., Tanaka, T., Standley, D.M., Takagi, J., Kikutani, H.
Clonal evolution and antigen-recognition of anti-nuclear antibodies in acute systemic lupus erythematosus 
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

H 3

Cell Constants:

a = 147.515   b = 147.515   c = 112.807 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.8.0124 program. The R value is 0.16359 for 50879 reflections in the resolution range 26.33 to 2.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)