A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 20-Sep-2017 number of released structures: 9123
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Polymer Type: All + RNA Type: All + Protein Function: All + Experimental Method: All + RNA Sequence Type: All RNA Sequence

Results: 3368  Download results as an excel file       Gallery view

NDB ID:

5LSN

PDB ID:

5LSN 

Release:

2017-09-20

Title:

SINEB2 element of the long non-coding RNA activator of translation AS Uchl1

Classification:

RNA

Authors:

Podbevsek, P., Fasolo, F., Bon, C., Cimatti, L., Reisser, S., Carninci, P., Bussi, G., Zucchelli, S., Plavec, J., Gustincich, S.

Citation:

Structural determinants of the SINEB2 element embedded in the long non-coding RNA activator of translation AS Uchl1
To Be Published pp. - 0

Experiment:

SOLUTION NMR

NDB ID:

5VAJ

PDB ID:

5VAJ 

Release:

2017-09-13

Title:

BhRNase H - amide-RNA/DNA complex

Classification:

hydrolase/rna/dna

Authors:

Mutisya, D., Hardcastle, T., Cheruiyot, S.K., Pallan, P.S., Kennedy, S.D., Egli, M., Kelley, M.L., Smith, A.V.B., Rozners, E.

Citation:

Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs.
Nucleic Acids Res. 45 pp.8142 - 8155 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.95Å R work:0.165R free:0.216

NDB ID:

5W1H

PDB ID:

5W1H 

Release:

2017-09-13

Title:

Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (24-nt spacer)

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Knott, G.J., East-Seletsky, A., Cofsky, J.C., Holton, J.M., Charles, E., Doudna, J.A.

Citation:

Guide bound structures of a divergent RNA-targeting A cleaving CRISPR-Cas13a enzyme
Nat.Struct.Mol.Biol. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.99Å R work:0.185R free:0.216

NDB ID:

5W1I

PDB ID:

5W1I 

Release:

2017-09-13

Title:

Crystal structure of LbaCas13a (C2c2) bound to mature crRNA (20-nt spacer)

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Knott, G.J., East-Seletsky, A., Cofsky, J.C., Holton, J.M., Charles, E., Doudna, J.A.

Citation:

Guide bound structures of a divergent RNA-targeting A cleaving CRISPR-Cas13a enzyme
Nat.Struct.Mol.Biol. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.2Å R work:0.196R free:0.232

NDB ID:

5WLH

PDB ID:

5WLH 

Release:

2017-09-13

Title:

Crystal structure of LbaCas13a H328A (C2c2) bound to pre-crRNA (24-nt spacer)

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Knott, G.J., East-Seletsky, A., Cofsky, J.C., Holton, J.M., Charles, E., Doudna, J.A.

Citation:

Guide bound structures of a divergent RNA-targeting A cleaving CRISPR-Cas13a enzyme
Nat.Struct.Mol.Biol. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.80001Å R work:0.184R free:0.217

NDB ID:

5XWP

PDB ID:

5XWP 

Release:

2017-09-13

Title:

Crystal structure of LbuCas13a-crRNA-target RNA ternary complex

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Liu, L., Li, X., Ma, J., Li, Z., You, L., Wang, J., Wang, M., Zhang, X., Wang, Y.

Citation:

The Molecular Architecture for RNA-Guided RNA Cleavage by Cas13a.
Cell 170 pp.714 - 726.e10 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.086Å R work:0.218R free:0.243

NDB ID:

5OR0

PDB ID:

5OR0 

Release:

2017-08-30

Title:

NMR derived model of the 5'-splice site of SMN2 in complex with the 5'-end of U1 snRNA

Classification:

RNA

Authors:

Sivaramakrishnan, M., McCarthy, K.D., Campagne, S., Huber, S., Meier, S., Augustin, A., Heckel, T., Meistermann, H., Hug, M.N., Birrer, P., Moursy, A., Khawaja, S., Schmucki, R., Berntenis, N., Giroud, N., Golling, S., Tzouros, N., Banfai, B., Duran-Pacheco, G., Lamerz, J., Hsiu Liu, Y., Luebbers, T., Ratni, A., Ebeling, M., Clery, A., Paushkin, S., Krainer, A.R., Allain, F.H., Metzger, F.

Citation:

Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers
Nat Commun pp. - 2017

Experiment:

SOLUTION NMR

NDB ID:

5W4K

PDB ID:

5W4K 

Release:

2017-08-30

Title:

Crystal structure of the Thermus thermophilus 70S ribosome in complex with Klebsazolicin and bound to mRNA and A-, P- and E-site tRNAs at 2.7A resolution

Classification:

ribosome/antibiotic

Authors:

Metelev, M., Osterman, I.A., Ghilarov, D., Khabibullina, N.F., Yakimov, A., Shabalin, K., Utkina, I., Travin, D.Y., Komarova, E.S., Serebryakova, M., Artamonova, T., Khodorkovskii, M., Konevega, A.L., Sergiev, P.V., Severinov, K., Polikanov, Y.S.

Citation:

Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Nat. Chem. Biol. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.206R free:0.252

NDB ID:

5KW1

PDB ID:

5KW1 

Release:

2017-08-23

Title:

Crystal Structure of the Two Tandem RRM Domains of PUF60 Bound to a Modified AdML Pre-mRNA 3' Splice Site Analogue

Classification:

splicing/dna

Authors:

Hsiao, H.-H., Crichlow, G.V., Albright, R.A., Murphy, J.W., Folta-Stogniew, E.J., Lolis, E.J., Braddock, D.T.

Citation:

Recognition of the 3' AdML intron by the alternative splicing factor PUF60
To be published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.1Å R work:0.219R free:0.237

NDB ID:

5WWW

PDB ID:

5WWW 

Release:

2017-08-23

Title:

Crystal structure of the KH1 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Yang, L., Wang, C., Li, F., Zhang, J., Nayab, A., Wu, J., Shi, Y., Gong, Q.

Citation:

The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.798Å R work:0.172R free:0.209

NDB ID:

5WWX

PDB ID:

5WWX 

Release:

2017-08-23

Title:

Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Yang, L., Wang, C., Li, F., Zhang, J., Nayab, A., Wu, J., Shi, Y., Gong, Q.

Citation:

The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity
J. Biol. Chem. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.0Å R work:0.17R free:0.217

NDB ID:

5O6U

PDB ID:

5O6U 

Release:

2017-08-16

Title:

Structure of the Cascade-I-Fv R-loop complex from Shewanella putrefaciens

Classification:

ANTIVIRAL PROTEIN

Authors:

Pausch, P., Muller-Esparza, H., Gleditzsch, D., Altegoer, F., Randau, L., Bange, G.

Citation:

Structural Variation of Type I-F CRISPR RNA Guided DNA Surveillance.
Mol. Cell 67 pp.622 - 632.e4 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.25Å R work:0.252R free:0.285

NDB ID:

5O7H

PDB ID:

5O7H 

Release:

2017-08-16

Title:

Structure of the Cascade-I-Fv complex from Shewanella putrefaciens

Classification:

ANTIVIRAL PROTEIN

Authors:

Pausch, P., Muller-Esparza, H., Gleditzsch, D., Altegoer, F., Randau, L., Bange, G.

Citation:

Structural Variation of Type I-F CRISPR RNA Guided DNA Surveillance.
Mol. Cell 67 pp.622 - 632.e4 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.0Å R work:0.221R free:0.267

NDB ID:

5VXQ

PDB ID:

5VXQ 

Release:

2017-08-16

Title:

X-Ray crystallography structure of the parallel stranded duplex formed by 5-rA5-dA-rA5

Classification:

RNA, DNA

Authors:

Copp, W., Denisov, A., Gehring, K., Liczner, C., Noronha, A., Safaee, N., Wilds, C., Xie, J.

Citation:

Influence of Nucleotide Modifications at the C2' Position on the Hoogsteen Base-Paired Parallel-Stranded Duplex of Poly(A) RNA
Nucleic Acids Res. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.002Å R work:0.128R free:0.159

NDB ID:

5XOG

PDB ID:

5XOG 

Release:

2017-08-16

Title:

RNA Polymerase II elongation complex bound with Spt5 KOW5 and Elf1

Classification:

TRANSCRIPTION

Authors:

Ehara, H., Yokoyama, T., Shigematsu, H., Yokoyama, S., Shirouzu, M., Sekine, S.I.

Citation:

Structure of the complete elongation complex of RNA polymerase II with basal factors
Science 357 pp.921 - 924 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.0Å R work:0.195R free:0.225

NDB ID:

5NRG

PDB ID:

5NRG 

Release:

2017-08-09

Title:

The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with RB02

Classification:

RIBOSOME

Authors:

Matzov, D., Eyal, Z., Ben Hamou, R.I., Halfon, Y., Krupkin, M., Zimmerman, E., Rozenberg, H., Bashan, A., Fridman, M., Yonath, A.

Citation:

Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus
Nucleic Acids Res. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.442Å R work:0.218R free:0.261

NDB ID:

5TGG

PDB ID:

5TGG 

Release:

2017-08-09

Title:

Solution structure of parallel stranded adenosine duplex

Classification:

RNA,DNA

Authors:

Copp, W., Denisov, A., Xie, J., Noronha, A., Liczner, C., Safaee, N., Wilds, C., Gehring, K.

Citation:

Influence of Nucleotide Modifications at the C2' Position on the Hoogsteen Base-Paired Parallel-Stranded Duplex of Poly(A) RNA
Nucleic Acids Res. pp. - 2017

Experiment:

SOLUTION NMR

NDB ID:

5WJR

PDB ID:

5WJR 

Release:

2017-08-09

Title:

2-Se-T2/4-DNA and native RNA hybrid in complex with RNase H catalytic domain D132N mutant

Classification:

HYDROLASE

Authors:

Fang, Z., Huang, Z.

Citation:

RNase H catalytic domain D132N mutant in complex with native DNA/RNA at 1.70 angstroms
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.7Å R work:0.188R free:0.233

NDB ID:

5XUS

PDB ID:

5XUS 

Release:

2017-08-09

Title:

Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (TTTA PAM)

Classification:

HYDROLASE/RNA/DNA

Authors:

Yamano, T., Zetsche, B., Ishitani, R., Zhang, F., Nishimasu, H., Nureki, O.

Citation:

Structural basis for the canonical and non-canonical PAM recognition by CRISPR-Cpf1
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.5Å R work:0.178R free:0.227

NDB ID:

5XUT

PDB ID:

5XUT 

Release:

2017-08-09

Title:

Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (TCTA PAM)

Classification:

HYDROLASE/RNA/DNA

Authors:

Yamano, T., Zetsche, B., Ishitani, R., Zhang, F., Nishimasu, H., Nureki, O.

Citation:

Structural basis for the canonical and non-canonical PAM recognition by CRISPR-Cpf1
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.4Å R work:0.192R free:0.237

NDB ID:

5XUU

PDB ID:

5XUU 

Release:

2017-08-09

Title:

Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (TCCA PAM)

Classification:

HYDROLASE/RNA/DNA

Authors:

Yamano, T., Zetsche, B., Ishitani, R., Zhang, F., Nishimasu, H., Nureki, O.

Citation:

Structural basis for the canonical and non-canonical PAM recognition by CRISPR-Cpf1
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.5Å R work:0.192R free:0.244

NDB ID:

5XUZ

PDB ID:

5XUZ 

Release:

2017-08-09

Title:

Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (CCCA PAM)

Classification:

HYDROLASE/RNA/DNA

Authors:

Yamano, T., Zetsche, B., Ishitani, R., Zhang, F., Nishimasu, H., Nureki, O.

Citation:

Structural basis for the canonical and non-canonical PAM recognition by CRISPR-Cpf1
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.4Å R work:0.177R free:0.229

NDB ID:

5O1Y

PDB ID:

5O1Y 

Release:

2017-08-02

Title:

Structure of Nrd1 RNA binding domain in complex with RNA (GUAA)

Classification:

TRANSCRIPTION

Authors:

Franco-Echevarria, E., Gonzalez-Polo, N., Zorrilla, S., Martinez-Lumbreras, S., Santiveri, C.M., Campos-Olivas, R., Sanchez, M., Calvo, O., Gonzalez, B., Perez-Canadillas, J.M.

Citation:

The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition
Nucleic Acids Res. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.45Å R work:0.196R free:0.217

NDB ID:

5O1Z

PDB ID:

5O1Z 

Release:

2017-08-02

Title:

Structure of Nrd1 RNA binding domain in complex with RNA (CGUAAA)

Classification:

TRANSCRIPTION

Authors:

Franco-Echevarria, E., Gonzalez-Polo, N., Zorrilla, S., Martinez-Lumbreras, S., Santiveri, C.M., Campos-Olivas, R., Sanchez, M., Calvo, O., Gonzalez, B., Perez-Canadillas, J.M.

Citation:

The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition
Nucleic Acids Res. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.4Å R work:0.181R free:0.215

NDB ID:

5O20

PDB ID:

5O20 

Release:

2017-08-02

Title:

Structure of Nrd1 RNA binding domain in complex with RNA (UUAGUAAUCC)

Classification:

TRANSCRIPTION

Authors:

Franco-Echevarria, E., Gonzalez-Polo, N., Zorrilla, S., Martinez-Lumbreras, S., Santiveri, C.M., Campos-Olivas, R., Sanchez, M., Calvo, O., Gonzalez, B., Perez-Canadillas, J.M.

Citation:

The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition
Nucleic Acids Res. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.53Å R work:0.225R free:0.268

NDB ID:

5U9B

PDB ID:

5U9B 

Release:

2017-08-02

Title:

Solution structure of the zinc fingers 1 and 2 of MBNL1 in complex with human cardiac troponin T pre-mRNA

Classification:

RNA BINDING PROTEIN/RNA

Authors:

Park, S., Phukan, P.D., Zeeb, M., Martinez-Yamout, M.A., Dyson, H.J., Wright, P.E.

Citation:

Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry 56 pp.4154 - 4168 2017

Experiment:

SOLUTION NMR

NDB ID:

5VZJ

PDB ID:

5VZJ 

Release:

2017-08-02

Title:

STRUCTURE OF A TWELVE COMPONENT MPP6-NUCLEAR RNA EXOSOME COMPLEX BOUND TO RNA

Classification:

HYDROLASE/RNA

Authors:

Wasmuth, E.V., Zinder, J.C., Zattas, D., Das, M., Lima, C.D.

Citation:

Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase.
Elife 6 pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.3Å R work:0.216R free:0.265

NDB ID:

5NQI

PDB ID:

5NQI 

Release:

2017-07-26

Title:

E.coli 16S rRNA Sarcin-Ricin Loop containing a 5-hydroxymethylcytosine modification

Classification:

RNA

Authors:

Riml, C., Lusser, A., Ennifar, E., Micura, R.

Citation:

Synthesis, Thermodynamic Properties, and Crystal Structure of RNA Oligonucleotides Containing 5-Hydroxymethylcytosine.
J. Org. Chem. 82 pp.7939 - 7945 2017

Experiment:

X-RAY DIFFRACTION Resolution:0.851Å R work:0.145R free:0.17

NDB ID:

5TBW

PDB ID:

5TBW 

Release:

2017-07-26

Title:

Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome

Classification:

RIBOSOME

Authors:

Konst, Z.A., Szklarski, A.R., Pellegrino, S., Michalak, S.E., Meyer, M., Zanette, C., Cencic, R., Nam, S., Voora, V.K., Horne, D.A., Pelletier, J., Mobley, D.L., Yusupova, G., Yusupov, M., Vanderwal, C.D.

Citation:

Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides
Nat.Chem. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.0Å R work:0.193R free:0.226

NDB ID:

5V2R

PDB ID:

5V2R 

Release:

2017-07-26

Title:

Structure of a GA Rich 8x8 Nucleotide RNA Internal Loop

Classification:

RNA

Authors:

Kauffmann, A.D., Kennedy, S.D., Zhao, J., Turner, D.H.

Citation:

Nuclear Magnetic Resonance Structure of an 8 8 Nucleotide RNA Internal Loop Flanked on Each Side by Three Watson-Crick Pairs and Comparison to Three-Dimensional Predictions.
Biochemistry 56 pp.3733 - 3744 2017

Experiment:

SOLUTION NMR

NDB ID:

5VI5

PDB ID:

5VI5 

Release:

2017-07-26

Title:

Structure of Mycobacterium smegmatis transcription initiation complex with a full transcription bubble

Classification:

TRANSCRIPTION

Authors:

Hubin, E.A., Lilic, M., Darst, S.A., Campbell, E.A.

Citation:

Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures.
Nat Commun 8 pp.16072 - 16072 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.196Å R work:0.253R free:0.279

NDB ID:

5W6V

PDB ID:

5W6V 

Release:

2017-07-26

Title:

The Structure of human Argonaute-1 in complex with the hook motif of human GW182

Classification:

GENE REGULATION/RNA

Authors:

Elkayam, E., Faehnle, C.R., Morales, M., Sun, J., Li, H., Joshua-Tor, L.

Citation:

Multivalent Recruitment of Human Argonaute by GW182.
Mol. Cell 67 pp.646 - 658.e3 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.828Å R work:0.2R free:0.244

NDB ID:

5KH8

PDB ID:

5KH8 

Release:

2017-07-19

Title:

Solution structures of the apo state fluoride riboswitch

Classification:

RNA

Authors:

Zhao, B., Guffy, S.L., Williams, B., Zhang, Q.

Citation:

An excited state underlies gene regulation of a transcriptional riboswitch.
Nat. Chem. Biol. 13 pp.968 - 974 2017

Experiment:

SOLUTION NMR

NDB ID:

5VYC

PDB ID:

5VYC 

Release:

2017-07-19

Title:

Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1.

Classification:

RIBOSOME

Authors:

Lomakin, I.B., Stolboushkina, E.A., Vaidya, A.T., Zhao, C., Garber, M.B., Dmitriev, S.E., Steitz, T.A.

Citation:

Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1.
Cell Rep 20 pp.521 - 528 2017

Experiment:

X-RAY DIFFRACTION Resolution:6.0Å R work:0.322R free:0.32

NDB ID:

5W5H

PDB ID:

5W5H 

Release:

2017-07-19

Title:

Human IFIT1 dimer with m7Gppp-AAAA

Classification:

RNA binding protein/RNA

Authors:

Abbas, Y.M., Martinez-Montero, S., Cencic, R., Pelletier, J., Damha, M.J., Pawelek, P.D., Nagar, B.

Citation:

Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.79Å R work:0.218R free:0.24

NDB ID:

5V16

PDB ID:

5V16 

Release:

2017-07-12

Title:

HnRNP A1 Alters the Conformation of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation

Classification:

RNA

Authors:

Tolbert, M., Morgan, C.E., Pollum, M., Crespo-Hernandez, C.E., Li, M.L., Brewer, G., Tolbert, B.S.

Citation:

HnRNP A1 Alters the Structure of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation.
J. Mol. Biol. pp. - 2017

Experiment:

SOLUTION NMR

NDB ID:

5V17

PDB ID:

5V17 

Release:

2017-07-12

Title:

HnRNP A1 Alters the Conformation of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation

Classification:

RNA

Authors:

Tolbert, M., Morgan, C.E., Pollum, M., Crespo-Hernandez, C.E., Li, M.L., Brewer, G., Tolbert, B.S.

Citation:

HnRNP A1 Alters the Structure of a Conserved Enterovirus IRES Domain to Stimulate Viral Translation.
J. Mol. Biol. pp. - 2017

Experiment:

SOLUTION NMR

NDB ID:

5MPG

PDB ID:

5MPG 

Release:

2017-07-05

Title:

Solution NMR structure of hnRNP A1 RRM1 in complex with 5'-UUAGGUC-3' RNA

Classification:

SPLICING

Authors:

Beusch, I., Barraud, P., Moursy, A., Clery, A., Allain, F.H.

Citation:

Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife 6 pp. - 2017

Experiment:

SOLUTION NMR

NDB ID:

5MPL

PDB ID:

5MPL 

Release:

2017-07-05

Title:

hnRNP A1 RRM2 in complex with 5'-UCAGUU-3' RNA

Classification:

SPLICING

Authors:

Beusch, I., Barraud, P., Moursy, A., Clery, A., Allain, F.H.

Citation:

Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7.
Elife 6 pp. - 2017

Experiment:

SOLUTION NMR

NDB ID:

5O3J

PDB ID:

5O3J 

Release:

2017-07-05

Title:

Crystal structure of TIA-1 RRM2 in complex with RNA

Classification:

RNA BINDING PROTEIN

Authors:

Sonntag, M., Jagtap, P.K.A., Simon, B., Appavou, M.S., Geerlof, A., Stehle, R., Gabel, F., Hennig, J., Sattler, M.

Citation:

Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins.
Angew. Chem. Int. Ed. Engl. 56 pp.9322 - 9325 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.97Å R work:0.25R free:0.311

NDB ID:

5T3K

PDB ID:

5T3K 

Release:

2017-07-05

Title:

Fluorescence detection of RNA-ligand binding and crystal structure determination of ribosomal decoding site RNA using a heavy atom containing fluorescent ribonucleoside

Classification:

RNA

Authors:

Nuthanakanti, A., Boerneke, M.A., Hermann, T., Srivatsan, S.G.

Citation:

Structure of the Ribosomal RNA Decoding Site Containing a Selenium-Modified Responsive Fluorescent Ribonucleoside Probe.
Angew. Chem. Int. Ed. Engl. 56 pp.2640 - 2644 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.142Å R work:0.197R free:0.246

NDB ID:

5TWS

PDB ID:

5TWS 

Release:

2017-07-05

Title:

Post-catalytic complex of human Polymerase Mu (H329A) with newly incorporated UTP

Classification:

TRANSFERASE/DNA

Authors:

Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme Polymerase Mu
Nucleic Acids Res. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.85Å R work:0.166R free:0.2

NDB ID:

5UED

PDB ID:

5UED 

Release:

2017-07-05

Title:

RNA primer-template complex with guanosine dinucleotide ligand G(5')pp(5')G

Classification:

RNA

Authors:

Zhang, W., Tam, C.P., Walton, T., Fahrenbach, A.C., Birrane, G., Szostak, J.W.

Citation:

Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Proc. Natl. Acad. Sci. U.S.A. 114 pp.7659 - 7664 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.5Å R work:0.21R free:0.232

NDB ID:

5UEE

PDB ID:

5UEE 

Release:

2017-07-05

Title:

RNA primer-template complex with guanosine dinucleotide ligand G(5')ppp(5')G

Classification:

RNA

Authors:

Zhang, W., Tam, C.P., Walton, T., Fahrenbach, A.C., Birrane, G., Szostak, J.W.

Citation:

Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Proc. Natl. Acad. Sci. U.S.A. 114 pp.7659 - 7664 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.9Å R work:0.231R free:0.274

NDB ID:

5UEF

PDB ID:

5UEF 

Release:

2017-07-05

Title:

RNA primer-template complex with guanosine dinucleotide p(5')G(3')p(5')G ligand

Classification:

RNA

Authors:

Zhang, W., Tam, C.P., Walton, T., Fahrenbach, A.C., Birrane, G., Szostak, J.W.

Citation:

Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Proc. Natl. Acad. Sci. U.S.A. 114 pp.7659 - 7664 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.1Å R work:0.239R free:0.303

NDB ID:

5UEG

PDB ID:

5UEG 

Release:

2017-07-05

Title:

RNA primer-template complex with guanosine dinucleotide G(5')pppp(5')G ligand

Classification:

RNA

Authors:

Zhang, W., Tam, C.P., Walton, T., Fahrenbach, A.C., Birrane, G., Szostak, J.W.

Citation:

Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.
Proc. Natl. Acad. Sci. U.S.A. 114 pp.7659 - 7664 2017

Experiment:

X-RAY DIFFRACTION Resolution:2.6Å R work:0.207R free:0.301

NDB ID:

5V3I

PDB ID:

5V3I 

Release:

2017-07-05

Title:

Crystal structure of the VS ribozyme - wild-type C634

Classification:

RNA

Authors:

DasGupta, S., Suslov, N.B., Piccirilli, J.A.

Citation:

Structural Basis for Substrate Helix Remodeling and Cleavage Loop Activation in the Varkud Satellite Ribozyme.
J. Am. Chem. Soc. 139 pp.9591 - 9597 2017

Experiment:

X-RAY DIFFRACTION Resolution:3.293Å R work:0.216R free:0.246

NDB ID:

5VZ8

PDB ID:

5VZ8 

Release:

2017-07-05

Title:

Post-catalytic complex of human Polymerase Mu (G433A) mutant with incoming UTP

Classification:

TRANSFERASE/DNA

Authors:

Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme Polymerase Mu
Nucleic Acids Res. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.601Å R work:0.171R free:0.193

NDB ID:

5VZB

PDB ID:

5VZB 

Release:

2017-07-05

Title:

Post-catalytic complex of human Polymerase Mu (G433S) mutant with incoming UTP

Classification:

TRANSFERASE/DNA

Authors:

Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme Polymerase Mu
Nucleic Acids Res. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.5Å R work:0.17R free:0.187

NDB ID:

5VZE

PDB ID:

5VZE 

Release:

2017-07-05

Title:

Post-catalytic complex of human Polymerase Mu (W434A) mutant with incoming UTP

Classification:

TRANSFERASE/DNA

Authors:

Moon, A.F., Pryor, J.M., Ramsden, D.A., Kunkel, T.A., Bebenek, K., Pedersen, L.C.

Citation:

Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme Polymerase Mu
Nucleic Acids Res. pp. - 2017

Experiment:

X-RAY DIFFRACTION Resolution:1.506Å R work:0.177R free:0.2