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As of 14-Nov-2018 number of released structures: 9899
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Polymer Type: All + Protein Function: All + Structural Features: All + Experimental Method: All

Results: 6718  Download results as an excel file       Gallery view

NDB ID:

5YBD

PDB ID:

5YBD 

Release:

2018-11-14

Title:

X-ray structure of ETS domain of Ergp55 in complex with E74DNA

Classification:

DNA BINDING PROTEIN

Authors:

Sharma, R., Gangwar, S.P., Saxena, A.K.

Citation:

Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence
Acta Crystallogr F Struct Biol Commun 74 pp.656 - 663 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.769Å R work:0.204R free:0.281

NDB ID:

5YUZ

PDB ID:

5YUZ 

Release:

2018-11-14

Title:

DNA polymerase IV - DNA ternary complex 11

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Kottur, J., Nair, D.T.

Citation:

Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction.
Nucleic Acids Res. 46 pp.5875 - 5885 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.83Å R work:0.197R free:0.232

NDB ID:

5YV0

PDB ID:

5YV0 

Release:

2018-11-14

Title:

DNA polymerase IV - DNA ternary complex 12

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Kottur, J., Nair, D.T.

Citation:

Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction.
Nucleic Acids Res. 46 pp.5875 - 5885 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.09Å R work:0.192R free:0.24

NDB ID:

6MC2

PDB ID:

6MC2 

Release:

2018-11-14

Title:

Crystal structure of a tetrameric DNA fold-back quadruplex

Classification:

DNA

Authors:

Chu, B., Zhang, D., Hwang, W., Paukstelis, P.J.

Citation:

Crystal structure of a tetrameric DNA fold-back quadruplex.
J. Am. Chem. Soc. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.05Å R work:0.106R free:0.137

NDB ID:

6MC3

PDB ID:

6MC3 

Release:

2018-11-14

Title:

Crystal structure of a tetrameric DNA fold-back quadruplex

Classification:

DNA

Authors:

Chu, B., Zhang, D., Hwang, W., Paukstelis, P.J.

Citation:

Crystal structure of a tetrameric DNA fold-back quadruplex.
J. Am. Chem. Soc. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.57Å R work:0.2R free:0.243

NDB ID:

6MC4

PDB ID:

6MC4 

Release:

2018-11-14

Title:

Crystal structure of a tetrameric DNA fold-back quadruplex

Classification:

DNA

Authors:

Chu, B., Zhang, D., Hwang, W., Paukstelis, P.J.

Citation:

Crystal structure of a tetrameric DNA fold-back quadruplex.
J. Am. Chem. Soc. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.25Å R work:0.228R free:0.268

NDB ID:

6MC5

PDB ID:

6MC5 

Release:

2018-11-14

Title:

Crystal structure of a tetrameric DNA fold-back quadruplex

Classification:

DNA

Authors:

Chu, B., Zhang, D., Hwang, W., Paukstelis, P.J.

Citation:

Crystal structure of a tetrameric DNA fold-back quadruplex.
J. Am. Chem. Soc. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.4Å R work:0.146R free:0.219

NDB ID:

5YUS

PDB ID:

5YUS 

Release:

2018-11-07

Title:

DNA polymerase IV - DNA ternary complex 2

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Kottur, J., Nair, D.T.

Citation:

Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res. 46 pp.5875 - 5885 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.94Å R work:0.189R free:0.227

NDB ID:

5YUW

PDB ID:

5YUW 

Release:

2018-11-07

Title:

DNA polymerase IV - DNA ternary complex 6

Classification:

DNA BINDING PROTEIN/DAN

Authors:

Kottur, J., Nair, D.T.

Citation:

Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res. 46 pp.5875 - 5885 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.124Å R work:0.188R free:0.231

NDB ID:

5YV3

PDB ID:

5YV3 

Release:

2018-11-07

Title:

DNA polymerase IV - DNA ternary complex 7

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Kottur, J., Nair, D.T.

Citation:

Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res. 46 pp.5875 - 5885 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.03Å R work:0.202R free:0.248

NDB ID:

5ZLV

PDB ID:

5ZLV 

Release:

2018-11-07

Title:

DNA polymerase IV - DNA ternary complex with 50mM MgCl2

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Kottur, J., Nair, D.T.

Citation:

Pyrophosphate hydrolysis is an intrinsic and critical step of the DNA synthesis reaction
Nucleic Acids Res. 46 pp.5875 - 5885 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.35Å R work:0.188R free:0.248

NDB ID:

6A47

PDB ID:

6A47 

Release:

2018-11-07

Title:

Structure of TREX2 in complex with a Y structured dsDNA

Classification:

DNA BINDING PROTEIN

Authors:

Cheng, H.L., Lin, C.T., Huang, K.W., Wang, S., Lin, Y.T., Toh, S.I., Hsiao, Y.Y.

Citation:

Structural insights into the duplex DNA processing of TREX2
Nucleic Acids Res. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.9Å R work:0.163R free:0.191

NDB ID:

6A4B

PDB ID:

6A4B 

Release:

2018-11-07

Title:

Structure of TREX2 in complex with a duplex DNA with 2 nucleotide 3'-overhang

Classification:

DNA BINDING PROTEIN

Authors:

Cheng, H.L., Lin, C.T., Huang, K.W., Wang, S., Lin, Y.T., Toh, S.I., Hsiao, Y.Y.

Citation:

Structural insights into the duplex DNA processing of TREX2
Nucleic Acids Res. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.224R free:0.263

NDB ID:

6E93

PDB ID:

6E93 

Release:

2018-11-07

Title:

Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 in complex with methylated DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Hudson, N.O., Whitby, F.G., Buck-Koehntop, B.A.

Citation:

Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38.
J. Biol. Chem. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.747Å R work:0.186R free:0.211

NDB ID:

6E94

PDB ID:

6E94 

Release:

2018-11-07

Title:

Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 K1055R in complex with methylated DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Hudson, N.O., Whitby, F.G., Buck-Koehntop, B.A.

Citation:

Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38.
J. Biol. Chem. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.594Å R work:0.193R free:0.218

NDB ID:

6GDH

PDB ID:

6GDH 

Release:

2018-11-07

Title:

Holliday Junctions formed from Telomeric DNA

Classification:

RECOMBINATION

Authors:

Haider, S., Li, P., Khiali, S., Munnur, D., Ramanathan, A., Parkinson, G.N.

Citation:

Holliday Junctions Formed from Human Telomeric DNA.
J. Am. Chem. Soc. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.85Å R work:0.228R free:0.272

NDB ID:

6GDN

PDB ID:

6GDN 

Release:

2018-11-07

Title:

Holliday Junctions formed from Telomeric DNA

Classification:

RECOMBINATION

Authors:

Haider, S., Li, P., Khiali, S., Munnur, D., Ramanathan, A., Parkinson, G.N.

Citation:

Holliday Junctions Formed from Human Telomeric DNA.
J. Am. Chem. Soc. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:3.0Å R work:0.234R free:0.279

NDB ID:

6GDS

PDB ID:

6GDS 

Release:

2018-11-07

Title:

Holliday Junctions formed from Telomeric DNA

Classification:

RECOMBINATION

Authors:

Haider, S., Li, P., Khiali, S., Munnur, D., Ramanathan, A., Parkinson, G.N.

Citation:

Holliday Junctions Formed from Human Telomeric DNA.
J. Am. Chem. Soc. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.95Å R work:0.242R free:0.286

NDB ID:

5WCU

PDB ID:

5WCU 

Release:

2018-10-31

Title:

Crystal structure of 167 bp nucleosome bound to the globular domain of linker histone H5

Classification:

CHROMATIN BINDING PROTEIN/DNA

Authors:

Zhou, B.R., Jiang, J., Ghirlando, R., Norouzi, D., Sathish Yadav, K.N., Feng, H., Wang, R., Zhang, P., Zhurkin, V., Bai, Y.

Citation:

Revisit of Reconstituted 30-nm Nucleosome Arrays Reveals an Ensemble of Dynamic Structures.
J. Mol. Biol. 430 pp.3093 - 3110 2018

Experiment:

X-RAY DIFFRACTION Resolution:5.53Å R work:0.188R free:0.238

NDB ID:

5Z6Z

PDB ID:

5Z6Z 

Release:

2018-10-31

Title:

Crystal structure of human DUX4 homeodomains bound to DNA

Classification:

TRANSCRIPTION/DNA

Authors:

Li, Y., Wu, B., Liu, H., Gao, Y., Yang, C., Chen, X., Zhang, J., Chen, Y., Gu, Y., Li, J., Ma, J., Gan, J.

Citation:

Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun. 505 pp.1161 - 1167 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.301Å R work:0.211R free:0.25

NDB ID:

5ZFW

PDB ID:

5ZFW 

Release:

2018-10-31

Title:

Crystal structure of human DUX4 homeodomains bound to A11G DNA mutant

Classification:

TRANSCRIPTION/DNA

Authors:

Li, Y., Wu, B., Liu, H., Gao, Y., Yang, C., Chen, X., Zhang, J., Chen, Y., Gu, Y., Li, J., Ma, J., Gan, J.

Citation:

Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun. 505 pp.1161 - 1167 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.103Å R work:0.192R free:0.227

NDB ID:

5ZFY

PDB ID:

5ZFY 

Release:

2018-10-31

Title:

Crystal structure of human DUX4 homeodomains bound to A12C DNA mutant

Classification:

TRANSCRIPTION/DNA

Authors:

Li, Y., Wu, B., Liu, H., Gao, Y., Yang, C., Chen, X., Zhang, J., Chen, Y., Gu, Y., Li, J., Ma, J., Gan, J.

Citation:

Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun. 505 pp.1161 - 1167 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.3Å R work:0.184R free:0.216

NDB ID:

5ZFZ

PDB ID:

5ZFZ 

Release:

2018-10-31

Title:

Crystal structure of human DUX4 homeodomains bound to A12T DNA mutant

Classification:

TRANSCRIPTION/DNA

Authors:

Li, Y., Wu, B., Liu, H., Gao, Y., Yang, C., Chen, X., Zhang, J., Chen, Y., Gu, Y., Li, J., Ma, J., Gan, J.

Citation:

Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun. 505 pp.1161 - 1167 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.9Å R work:0.185R free:0.221

NDB ID:

6AI6

PDB ID:

6AI6 

Release:

2018-10-31

Title:

Crystal structure of SpCas9-NG

Classification:

HYDROLASE/RNA/DNA

Authors:

Nishimasu, H., Shi, X., Ishiguro, S., Gao, L., Hirano, S., Okazaki, S., Noda, T., Abudayyeh, O.O., Gootenberg, J.S., Mori, H., Oura, S., Holmes, B., Tanaka, M., Seki, M., Hirano, H., Aburatani, H., Ishitani, R., Ikawa, M., Yachie, N., Zhang, F., Nureki, O.

Citation:

Engineered CRISPR-Cas9 nuclease with expanded targeting space
Science 361 pp.1259 - 1262 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.217R free:0.243

NDB ID:

6BEK

PDB ID:

6BEK 

Release:

2018-10-31

Title:

Structure of sIHF bound to an 8bp palindromic DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Nanji, T.N., Gehrke, E.J., Shen, Y., Gloyd, M., Kirby, C.D., Huynh, A., Razi, A., Ortega, J., Elliott, M.A., Guarne, A.

Citation:

Streptomyces IHF uses multiple interfaces to bind DNA and condense nucleoids
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.7Å R work:0.201R free:0.233

NDB ID:

6BEL

PDB ID:

6BEL 

Release:

2018-10-31

Title:

Ternary complex crystal structure of DNA polymerase Beta with R-isomer of beta-gamma-CHF-dCTP

Classification:

TRANSFERASE/DNA

Authors:

Batra, V.K., Oertell, K., Beard, W.A., Kashemirov, B.A., McKenna, C.E., Goodman, M.F., Wilson, S.H.

Citation:

Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry 57 pp.3934 - 3944 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.898Å R work:0.167R free:0.201

NDB ID:

6BEM

PDB ID:

6BEM 

Release:

2018-10-31

Title:

Ternary complex crystal structure of DNA polymerase Beta with S-isomer of beta-gamma-CHCL-dCTP

Classification:

TRANSFERASE/DNA

Authors:

Batra, V.K., Oertell, K., Beard, W.A., Kashemirov, B.A., McKenna, C.E., Goodman, M.F., Wilson, S.H.

Citation:

Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry 57 pp.3934 - 3944 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.88Å R work:0.187R free:0.226

NDB ID:

6BHJ

PDB ID:

6BHJ 

Release:

2018-10-31

Title:

Structure of HIV-1 Reverse Transcriptase Bound to a 38-mer Hairpin Template-Primer RNA-DNA Aptamer

Classification:

TRANSFERASE/DNA

Authors:

Tuske, S., Zheng, J., Olson, E.D., Ruiz, F.X., Pascal, B.D., Bauman, J.D., Das, K., DeStefano, J.J., Musier-Forsyth, K., Griffin, P.R., Arnold, E.

Citation:

Structure of HIV-1 Reverse Transcriptase Bound to a 38-mer Hairpin Template-Primer RNA-DNA Aptamer
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.81Å R work:0.203R free:0.244

NDB ID:

6DSU

PDB ID:

6DSU 

Release:

2018-10-31

Title:

Bst DNA polymerase I pre-insertion complex structure

Classification:

TRANSFERASE/DNA

Authors:

Chim, N., Jackson, L.N., Trinh, A.M., Chaput, J.C.

Citation:

Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife 7 pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.98Å R work:0.222R free:0.271

NDB ID:

6DSV

PDB ID:

6DSV 

Release:

2018-10-31

Title:

Bst DNA polymerase I post-chemistry (n+2) structure

Classification:

Transferase/DNA

Authors:

Chim, N., Jackson, L.N., Trinh, A.M., Chaput, J.C.

Citation:

Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife 7 pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.99Å R work:0.192R free:0.228

NDB ID:

6DSW

PDB ID:

6DSW 

Release:

2018-10-31

Title:

Bst DNA polymerase I pre-chemistry (n) structure

Classification:

TRANSFERASE/DNA

Authors:

Chim, N., Jackson, L.N., Trinh, A.M., Chaput, J.C.

Citation:

Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife 7 pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.589Å R work:0.165R free:0.189

NDB ID:

6DSX

PDB ID:

6DSX 

Release:

2018-10-31

Title:

Bst DNA polymerase I post-chemistry (n+1 with dATP soak) structure

Classification:

TRANSFERASE/DNA

Authors:

Chim, N., Jackson, L.N., Trinh, A.M., Chaput, J.C.

Citation:

Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife 7 pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.99Å R work:0.184R free:0.219

NDB ID:

6DSY

PDB ID:

6DSY 

Release:

2018-10-31

Title:

Bst DNA polymerase I post-chemistry (n+1) structure

Classification:

Transferase/DNA

Authors:

Chim, N., Jackson, L.N., Trinh, A.M., Chaput, J.C.

Citation:

Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway.
Elife 7 pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.98Å R work:0.202R free:0.254

NDB ID:

6EN8

PDB ID:

6EN8 

Release:

2018-10-31

Title:

SaFadR in complex with dsDNA

Classification:

TRANSCRIPTION

Authors:

Valegard, K., Lindas, A.-C., Peeters, E.

Citation:

A bacterial-like FadR transcription factor regulates lipid and fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius.
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.29Å R work:0.201R free:0.238

NDB ID:

6FK4

PDB ID:

6FK4 

Release:

2018-10-31

Title:

Structure of 3' phosphatase NExo (WT) from Neisseria bound to DNA substrate

Classification:

DNA BINDING PROTEIN

Authors:

Silhan, J., Zhao, Q., Boura, E., Thomson, H., Forster, A., Tang, C.M., Freemont, P.S., Baldwin, G.S.

Citation:

Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis.
Nucleic Acids Res. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.297Å R work:0.198R free:0.23

NDB ID:

6FK5

PDB ID:

6FK5 

Release:

2018-10-31

Title:

Structure of 3' phosphatase NExo (D146N) from Neisseria bound to DNA substrate in presence of magnesium ion

Classification:

DNA BINDING PROTEIN

Authors:

Silhan, J., Zhao, Q., Boura, E., Thomson, H., Forster, A., Tang, C.M., Freemont, P.S., Baldwin, G.S.

Citation:

Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis.
Nucleic Acids Res. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.02Å R work:0.23R free:0.257

NDB ID:

6FKE

PDB ID:

6FKE 

Release:

2018-10-31

Title:

Structure of 3' phosphatase NExo (D146N) from Neisseria bound to product DNA hairpin

Classification:

DNA BINDING PROTEIN

Authors:

Silhan, J., Zhao, Q., Boura, E., Thomson, H., Forster, A., Tang, C.M., Freemont, P.S., Baldwin, G.S.

Citation:

Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis.
Nucleic Acids Res. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.151Å R work:0.2R free:0.224

NDB ID:

6HKT

PDB ID:

6HKT 

Release:

2018-10-31

Title:

Structure of an H1-bound 6-nucleosome array

Classification:

DNA BINDING PROTEIN

Authors:

Garcia-Saez, I., Menoni, H., Boopathi, R., Shukla, M.S., Soueidan, L., Noirclerc-Savoye, M., Le Roy, A., Skoufias, D.A., Bednar, J., Hamiche, A., Angelov, D., Petosa, C., Dimitrov, S.

Citation:

Structure of an H1-Bound 6-Nucleosome Array Reveals an Untwisted Two-Start Chromatin Fiber Conformation.
Mol. Cell pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:9.7Å R work:0.253R free:0.286

NDB ID:

5W77

PDB ID:

5W77 

Release:

2018-10-24

Title:

Complex of DNA and compounds

Classification:

DNA/INHIBITOR

Authors:

Calabrese, D.R., Chen, X., Leon, E.C., Gaikwad, S.M., Phyo, Z., Hewitt, W.M., Alden, S., Hilimire, T.A., He, F., Michalowski, A.M., Simmons, J.K., Saunders, L.B., Zhang, S., Connors, D., Walters, K.J., Mock, B.A., Schneekloth Jr., J.S.

Citation:

Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.
Nat Commun 9 pp.4229 - 4229 2018

Experiment:

SOLUTION NMR

NDB ID:

6A8R

PDB ID:

6A8R 

Release:

2018-10-24

Title:

Crystal structure of DUX4 HD2 domain associated with ERG DNA binding site

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Dong, X., Zhang, H., Cheng, N., Li, K., Meng, G.

Citation:

DUX4HD2-DNAERGstructure reveals new insight into DUX4-Responsive-Element
Leukemia pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.6Å R work:0.2R free:0.207

NDB ID:

6BCE

PDB ID:

6BCE 

Release:

2018-10-24

Title:

Wild-type I-LtrI bound to cognate substrate (pre-cleavage complex)

Classification:

HYDROLASE/DNA

Authors:

McMurrough, T.A., Brown, C.M., Zhang, K., Hausner, G., Junop, M.S., Gloor, G.B., Edgell, D.R.

Citation:

Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.
Nucleic Acids Res. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:1.75Å R work:0.201R free:0.225

NDB ID:

6BCF

PDB ID:

6BCF 

Release:

2018-10-24

Title:

I-LtrI G183A bound to cognate substrate (pre-cleavage complex)

Classification:

HYDROLASE/DNA

Authors:

McMurrough, T.A., Brown, C.M., Zhang, K., Hausner, G., Junop, M.S., Gloor, G.B., Edgell, D.R.

Citation:

Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.
Nucleic Acids Res. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.92Å R work:0.239R free:0.308

NDB ID:

6BCG

PDB ID:

6BCG 

Release:

2018-10-24

Title:

I-LtrI A28G bound to cognate substrate (pre-cleavage complex)

Classification:

HYDROLASE/DNA

Authors:

McMurrough, T.A., Brown, C.M., Zhang, K., Hausner, G., Junop, M.S., Gloor, G.B., Edgell, D.R.

Citation:

Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.
Nucleic Acids Res. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.9Å R work:0.262R free:0.306

NDB ID:

6BCH

PDB ID:

6BCH 

Release:

2018-10-24

Title:

I-LtrI E29D bound to cognate substrate (nicked complex)

Classification:

HYDROLASE/DNA

Authors:

McMurrough, T.A., Brown, C., Zhang, K., Junop, M., Gloor, G.B., Edgell, D.R.

Citation:

I-LtrI E29D bound to cognate substrate (nicked complex)
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:3.0Å R work:0.254R free:0.306

NDB ID:

6BCI

PDB ID:

6BCI 

Release:

2018-10-24

Title:

Wild-type I-LtrI bound to non-cognate C4 substrate (pre-cleavage complex)

Classification:

HYDROLASE/DNA

Authors:

McMurrough, T.A., Brown, C.M., Zhang, K., Hausner, G., Junop, M.S., Gloor, G.B., Edgell, D.R.

Citation:

Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.
Nucleic Acids Res. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.28Å R work:0.237R free:0.268

NDB ID:

6BCN

PDB ID:

6BCN 

Release:

2018-10-24

Title:

I-LtrI E184D bound to cognate substrate (pre-cleavage complex)

Classification:

HYDROLASE/DNA

Authors:

McMurrough, T.A., Brown, C.M., Zhang, K., Hausner, G., Junop, M.S., Gloor, G.B., Edgell, D.R.

Citation:

Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.
Nucleic Acids Res. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.5Å R work:0.237R free:0.276

NDB ID:

6BCT

PDB ID:

6BCT 

Release:

2018-10-24

Title:

I-LtrI E184D bound to non-cognate C4 substrate (pre-cleavage complex)

Classification:

HYDROLASE/DNA

Authors:

McMurrough, T.A., Brown, C.M., Zhang, K., Hausner, G., Junop, M.S., Gloor, G.B., Edgell, D.R.

Citation:

Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.
Nucleic Acids Res. pp. - 2018

Experiment:

X-RAY DIFFRACTION Resolution:2.73Å R work:0.226R free:0.281

NDB ID:

6BD0

PDB ID:

6BD0 

Release:

2018-10-24

Title:

I-OnuI K227Y, D236A bound to cognate substrate (pre-cleavage complex)

Classification:

HYDROLASE/DNA

Authors:

Laforet, M., McMurrough, T.A., Brown, C., Zhang, K., Junop, M., Gloor, G.B., Edgell, D.R.

Citation:

I-OnuI K227Y, D236A bound to cognate substrate (pre-cleavage complex)
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.45Å R work:0.164R free:0.189

NDB ID:

6BDA

PDB ID:

6BDA 

Release:

2018-10-24

Title:

Wild-type I-OnuI bound to A3G substrate (post-cleavage complex)

Classification:

HYDROLASE/DNA

Authors:

Laforet, M., McMurrough, T., Brown, C., Zhang, K., Junop, M., Gloor, G.B., Edgell, D.R.

Citation:

Wild-type I-OnuI bound to A3G substrate (post-cleavage complex)
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.88Å R work:0.191R free:0.232

NDB ID:

6BDB

PDB ID:

6BDB 

Release:

2018-10-24

Title:

I-OnuI K227Y, D236A bound to A3G substrate (pre-cleavage complex)

Classification:

HYDROLASE

Authors:

Laforet, M., McMurrough, T.A., Brown, C., Junop, M., Zhang, K., Gloor, G.B.

Citation:

I-OnuI K227Y, D236A bound to A3G substrate (pre-cleavage complex)
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.5Å R work:0.185R free:0.206