A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 12-Aug-2022 number of released structures: 12231
Search for released structures

DNA Search Options:

Polymer

All
DNA Only
Protein DNA Complexes
Drug DNA Complexes
Hybrids and Chimera
Peptide Nucleic Acid / Mimetics

Protein Function

All
Enzymes
Structural
Regulatory

Structural Features

All
Single Stranded
A DNA
B DNA
Z DNA
Other Double
       Helical Structures
Triple helices
Quadruple helices

Experimental Method

All
XRAY
NMR

Text Search

Filter results by text search

Use this option to narrow your results down considerably (>50% reduction) using any word seen in the results page. Eg: Any author name found in the right side



Polymer Type: All + Protein Function: All + Structural Features: All + Experimental Method: All

Results: 8374  Download results as an excel file       Gallery view

NDB ID:

7P9Z

PDB ID:

7P9Z 

Release:

2022-08-10

Title:

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing adenine opposite to lesion)

Classification:

HYDROLASE

Authors:

Coste, F., Goffinont, S., Flament, D., Castaing, B.

Citation:

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing adenine opposite to lesion)
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.33Å R work:0.173R free:0.186

NDB ID:

7TDW

PDB ID:

7TDW 

Release:

2022-08-10

Title:

Structure of FOXP3-DNA complex

Classification:

TRANSCRIPTION/DNA

Authors:

Leng, F., Zhang, W., Ramirez, R.N., Leon, J., Zhong, Y., Hou, L., Yuki, K., van der Veeken, J., Rudensky, A.Y., Benoist, C., Hur, S.

Citation:

The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis
Immunity pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:4.0Å R work:0.334R free:0.359

NDB ID:

7TDX

PDB ID:

7TDX 

Release:

2022-08-10

Title:

Structure of FOXP3-DNA complex

Classification:

TRANSCRIPTION/DNA

Authors:

Leng, F., Zhang, W., Ramirez, R.N., Leon, J., Zhong, Y., Hou, L., Yuki, K., van der Veeken, J., Rudensky, A.Y., Benoist, C., Hur, S.

Citation:

The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis
Immunity pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:3.1Å R work:0.297R free:0.314

NDB ID:

8CSH

PDB ID:

8CSH 

Release:

2022-08-10

Title:

Structure of the DNA binding domain of pSK1 Par partition protein bound to centromere DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Chan, H.Y., Jensen, S.O., LeBard, R.J., Figgett, W.A., Lai, E., Simpson, A.E., Brzoska, A.J., Davies, D.S., Connolly, A.M., Cordwell, S.J., Travis, B.A., Salinas, R., Skurray, R.A., Firth, N., Schumacher, M.A.

Citation:

Molecular Analysis of pSK1 par: A Novel Plasmid Partitioning System Encoded by Staphylococcal Multiresistance Plasmids.
J.Mol.Biol. pp.167770 - 167770 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.25Å R work:0.202R free:0.249

NDB ID:

7FGT

PDB ID:

7FGT 

Release:

2022-08-03

Title:

Discovery of DS15060524; Gene targeting chimera (GeneTAC) for the treatment of Friedreich's Ataxia (FRDA)

Classification:

DNA

Authors:

Igarashi, W., Takase, N., Kawai, G., Katagiri, T.

Citation:

Discovery of DS15060524; Gene targeting chimera (GeneTAC) for the treatment of Friedreich's Ataxia (FRDA)
To be published pp. - 0

Experiment:

SOLUTION NMR

NDB ID:

7OOO

PDB ID:

7OOO 

Release:

2022-08-03

Title:

The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG containing an LNA-Amide-LNA modification

Classification:

DNA-RNA HYBRID

Authors:

Baker, Y.R., Thorpe, C., Chen, J., Poller, L.M., Cox, L., Kumar, P., Lim, W.F., Lie, L., McClorey, G., Epple, S., Singleton, D., McDonough, M.A., Hardwick, J.S., Christensen, K.E., Wood, M.J.A., Hall, J.P., El-Sagheer, A.H., Brown, T.

Citation:

An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.
Nat Commun 13 pp.4036 - 4036 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.57Å R work:0.232R free:0.251

NDB ID:

7OOS

PDB ID:

7OOS 

Release:

2022-08-03

Title:

The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG

Classification:

DNA-RNA HYBRID

Authors:

Baker, Y.R., Thorpe, C., Chen, J., Poller, L.M., Cox, L., Kumar, P., Lim, W.F., Lie, L., McClorey, G., Epple, S., Singleton, D., McDonough, M.A., Hardwick, J.S., Christensen, K.E., Wood, M.J.A., Hall, J.P., El-Sagheer, A.H., Brown, T.

Citation:

An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.
Nat Commun 13 pp.4036 - 4036 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.6Å R work:0.217R free:0.234

NDB ID:

7OZZ

PDB ID:

7OZZ 

Release:

2022-08-03

Title:

The crystal structure of a DNA:RNA hybrid duplex sequence CTTTTCTTTG with LNA-amide modification

Classification:

DNA-RNA HYBRID

Authors:

Baker, Y.R., Thorpe, C., Chen, J., Poller, L.M., Cox, L., Kumar, P., Lim, W.F., Lie, L., McClorey, G., Epple, S., Singleton, D., McDonough, M.A., Hardwick, J.S., Christensen, K.E., Wood, M.J.A., Hall, J.P., El-Sagheer, A.H., Brown, T.

Citation:

An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.
Nat Commun 13 pp.4036 - 4036 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.2R free:0.236

NDB ID:

7P8L

PDB ID:

7P8L 

Release:

2022-08-03

Title:

Crystal structure of Pyrococcus abyssi 8-oxoguanine DNA glycosylase (PabAGOG) in complex with dsDNA containing cytosine opposite to 8-oxoG

Classification:

HYDROLASE

Authors:

Coste, F., Flament, D., Castaing, B.

Citation:

Crystal structure of Pyrococcus abyssi 8-oxoguanine DNA glycosylase (PabAGOG) in complex with dsDNA containing cytosine opposite to 8-oxoG
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.25Å R work:0.135R free:0.16

NDB ID:

7S03

PDB ID:

7S03 

Release:

2022-08-03

Title:

DNA-binding domain of human SETMAR in complex with Hsmar1 terminal inverted repeat (TIR) DNA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Chen, Q., Bates, A.M., Hanquier, J.N., Simpson, E., Rusch, D.B., Podicheti, R., Liu, Y., Wek, R.C., Cornett, E.M., Georgiadis, M.M.

Citation:

Structural and genome-wide analyses suggest that transposon-derived protein SETMAR alters transcription and splicing.
J.Biol.Chem. 298 pp.101894 - 101894 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.37Å R work:0.21R free:0.234

NDB ID:

7S9J

PDB ID:

7S9J 

Release:

2022-08-03

Title:

Crystal Structure of DNA Polymerase Beta with Fapy-dG base-paired with a dC

Classification:

DNA BNDING PROTEIN/DNA

Authors:

Ryan, B.J., Yang, H., Bacurio, J.H.T., Smith, M.R., Basu, A.K., Greenberg, M.M., Freudenthal, B.D.

Citation:

Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication.
J.Am.Chem.Soc. 144 pp.8054 - 8065 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.91Å R work:0.187R free:0.237

NDB ID:

7S9K

PDB ID:

7S9K 

Release:

2022-08-03

Title:

Crystal Structure of DNA Polymerase Beta with Fapy-dG base-paired with a dA

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Ryan, B.J., Yang, H., Bacurio, J.H.T., Smith, M.R., Basu, A.K., Greenberg, M.M., Freudenthal, B.D.

Citation:

Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication.
J.Am.Chem.Soc. 144 pp.8054 - 8065 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.97Å R work:0.171R free:0.224

NDB ID:

7S9L

PDB ID:

7S9L 

Release:

2022-08-03

Title:

Crystal Structure of DNA Polymerase Beta with Ring open intermediate Fapy-dG base-paired with a dC

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Ryan, B.J., Yang, H., Bacurio, J.H.T., Smith, M.R., Basu, A.K., Greenberg, M.M., Freudenthal, B.D.

Citation:

Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication.
J.Am.Chem.Soc. 144 pp.8054 - 8065 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.05Å R work:0.196R free:0.262

NDB ID:

7S9M

PDB ID:

7S9M 

Release:

2022-08-03

Title:

Crystal Structure of DNA Polymerase Beta with Ring open intermediate Fapy-dG base-paired with a dA

Classification:

DNA BINDING/DNA

Authors:

Ryan, B.J., Yang, H., Bacurio, J.H.T., Smith, M.R., Basu, A.K., Greenberg, M.M., Freudenthal, B.D.

Citation:

Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication.
J.Am.Chem.Soc. 144 pp.8054 - 8065 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.31Å R work:0.218R free:0.299

NDB ID:

7S9N

PDB ID:

7S9N 

Release:

2022-08-03

Title:

Binary complex of DNA Polymerase Beta with Fapy-dG in the template position

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Ryan, B.J., Yang, H., Bacurio, J.H.T., Smith, M.R., Basu, A.K., Greenberg, M.M., Freudenthal, B.D.

Citation:

Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication.
J.Am.Chem.Soc. 144 pp.8054 - 8065 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.71Å R work:0.191R free:0.236

NDB ID:

7S9O

PDB ID:

7S9O 

Release:

2022-08-03

Title:

Binary complex of DNA Polymerase Beta with Ring open Intermediate Fapy-dG in the template position

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Ryan, B.J., Yang, H., Bacurio, J.H.T., Smith, M.R., Basu, A.K., Greenberg, M.M., Freudenthal, B.D.

Citation:

Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication.
J.Am.Chem.Soc. 144 pp.8054 - 8065 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.23Å R work:0.201R free:0.277

NDB ID:

7S9P

PDB ID:

7S9P 

Release:

2022-08-03

Title:

Ternary complex of DNA Polymerase Beta with Template Fapy-dG and an incoming dCTP analog

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Ryan, B.J., Yang, H., Bacurio, J.H.T., Smith, M.R., Basu, A.K., Greenberg, M.M., Freudenthal, B.D.

Citation:

Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication.
J.Am.Chem.Soc. 144 pp.8054 - 8065 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.86Å R work:0.176R free:0.227

NDB ID:

7S9Q

PDB ID:

7S9Q 

Release:

2022-08-03

Title:

Ternary complex of DNA Polymerase Beta with Template Fapy-dG and an incoming dATP analog

Classification:

DNA BINDING PROTEIN/DNA

Authors:

Ryan, B.J., Yang, H., Bacurio, J.H.T., Smith, M.R., Basu, A.K., Greenberg, M.M., Freudenthal, B.D.

Citation:

Structural Dynamics of a Common Mutagenic Oxidative DNA Lesion in Duplex DNA and during DNA Replication.
J.Am.Chem.Soc. 144 pp.8054 - 8065 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.9Å R work:0.193R free:0.247

NDB ID:

7TQQ

PDB ID:

7TQQ 

Release:

2022-08-03

Title:

Structure of human TREX1-DNA complex

Classification:

HYDROLASE/DNA

Authors:

Zhou, W., Richmond-Buccola, D., Wang, Q., Kranzusch, P.J.

Citation:

Structural basis of human TREX1 DNA degradation and autoimmune disease.
Nat Commun 13 pp.4277 - 4277 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.2Å R work:0.226R free:0.26

NDB ID:

7BJQ

PDB ID:

7BJQ 

Release:

2022-07-27

Title:

Crystal structure of RecJCdc45 from Methanothermobacter thermoautotroficus in complex with ssDNA

Classification:

DNA BINDING PROTEIN

Authors:

De March, M., Onesti, S.

Citation:

Crystal structure of RecJCdc45 from Methanothermobacter thermoautotroficus
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.7Å R work:0.196R free:0.258

NDB ID:

7R3X

PDB ID:

7R3X 

Release:

2022-07-27

Title:

The crystal structure of the L439V variant of Pol2CORE in complex with DNA and an incoming nucleotide

Classification:

DNA BINDING PROTEIN

Authors:

Barbari, S.R., Beach, A.K., Markgren, J.G., Parkash, V., Moore, E.A., Johansson, E., Shcherbakova, P.V.

Citation:

Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase epsilon variants at low dNTP levels.
Nucleic Acids Res. pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.46Å R work:0.209R free:0.256

NDB ID:

7R3Y

PDB ID:

7R3Y 

Release:

2022-07-27

Title:

The crystal structure of the V426L variant of Pol2CORE in complex with DNA and an incoming nucleotide

Classification:

DNA BINDING PROTEIN

Authors:

Barbari, S.R., Beach, A.K., Markgren, J.G., Parkash, V., Moore, E.A., Johansson, E., Shcherbakova, P.V.

Citation:

Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase epsilon variants at low dNTP levels.
Nucleic Acids Res. pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.6Å R work:0.22R free:0.27

NDB ID:

7R6R

PDB ID:

7R6R 

Release:

2022-07-20

Title:

Crystal Structure of a Mycobacteriophage Cluster A2 Immunity Repressor:DNA Complex

Classification:

GENE REGULATION/DNA

Authors:

McGinnis, R.J., Brambley, C.A., Stamey, B., Green, W.C., Gragg, K.N., Cafferty, E.R., Terwilliger, T.C., Hammel, M., Hollis, T.J., Miller, J.M., Gainey, M.D., Wallen, J.R.

Citation:

A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence.
Nat Commun 13 pp.4105 - 4105 2022

Experiment:

X-RAY DIFFRACTION Resolution:3.13Å R work:0.208R free:0.247

NDB ID:

7SR6

PDB ID:

7SR6 

Release:

2022-07-20

Title:

Human Endogenous Retrovirus (HERV-K) reverse transcriptase ternary complex with dsDNA template Primer and dNTP

Classification:

REPLICATION

Authors:

Baldwin, E.T., Gotte, M., Tchesnokov, E.P., Arnold, E., Hagel, M., Nichols, C., Dossang, P., Lamers, M., Wan, P., Steinbacher, S., Romero, D.L.

Citation:

Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition.
Proc.Natl.Acad.Sci.USA 119 pp.e2200260119 - e2200260119 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.62Å R work:0.167R free:0.218

NDB ID:

7TZ1

PDB ID:

7TZ1 

Release:

2022-07-20

Title:

Crystal Structure of a Mycobacteriophage Cluster A2 Immunity Repressor:DNA Complex

Classification:

GENE REGULATION/DNA

Authors:

McGinnis, R.J., Brambley, C.A., Stamey, B., Green, W.C., Gragg, K.N., Cafferty, E.R., Terwilliger, T.C., Hammel, M., Hollis, T.J., Miller, J.M., Gainey, M.D., Wallen, J.R.

Citation:

A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence.
Nat Commun 13 pp.4105 - 4105 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.79Å R work:0.198R free:0.245

NDB ID:

7XQ5

PDB ID:

7XQ5 

Release:

2022-07-20

Title:

Crystal structure of ScIno2p-ScIno4p bound promoter DNA

Classification:

TRANSCRIPTION

Authors:

Khan, M.H., Xue, L., Yue, J., Schuller, H.J., Zhu, Z., Niu, L.

Citation:

Structural Analysis of Ino2p/Ino4p Mutual Interactions and Their Binding Interface with Promoter DNA.
Int J Mol Sci 23 pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.25Å R work:0.213R free:0.234

NDB ID:

7BCA

PDB ID:

7BCA 

Release:

2022-07-13

Title:

Crystal structure of the HTH DNA binding protein ArdK from R388 plasmid bound to a direct-repeat DNA element

Classification:

DNA BINDING PROTEIN

Authors:

Fernandez-Lopez, R., Boer, D.R., Moncalian, G.

Citation:

Crystal structure of the HTH DNA binding protein ArdK from R388 plasmid bound to a direct-repeat DNA element
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.231R free:0.292

NDB ID:

7OY7

PDB ID:

7OY7 

Release:

2022-07-13

Title:

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion)

Classification:

HYDROLASE

Authors:

Coste, F., Goffinont, S., Flament, D., Castaing, B.

Citation:

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion)
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.7Å R work:0.166R free:0.205

NDB ID:

7P0W

PDB ID:

7P0W 

Release:

2022-07-13

Title:

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing thymine opposite to lesion)

Classification:

HYDROLASE

Authors:

Coste, F., Goffinont, S., Flament, D., Castaing, B.

Citation:

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing thymine opposite to lesion)
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:1.12Å R work:0.123R free:0.143

NDB ID:

7SUM

PDB ID:

7SUM 

Release:

2022-07-13

Title:

Crystal structure of human ligase I with nick duplexes containing cognate A:T

Classification:

LIGASE/DNA

Authors:

Tang, Q., Gulkis, M., McKenna, R., Caglayan, M.

Citation:

Structures of LIG1 that engage with mutagenic mismatches inserted by pol beta in base excision repair.
Nat Commun 13 pp.3860 - 3860 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.9Å R work:0.18R free:0.226

NDB ID:

7SX5

PDB ID:

7SX5 

Release:

2022-07-13

Title:

Crystal structure of ligase I with nick duplexes containing mismatch A:C

Classification:

LIGASE

Authors:

Tang, Q., Gulkis, M., McKenna, R., Caglayan, M.

Citation:

Structures of LIG1 that engage with mutagenic mismatches inserted by pol beta in base excision repair.
Nat Commun 13 pp.3860 - 3860 2022

Experiment:

X-RAY DIFFRACTION Resolution:2.8Å R work:0.175R free:0.211

NDB ID:

7SXE

PDB ID:

7SXE 

Release:

2022-07-13

Title:

Crystal structure of ligase I with nick duplexes containing cognate G:T

Classification:

LIGASE/DNA

Authors:

Tang, Q., Gulkis, M., McKenna, R., Caglayan, M.

Citation:

Structures of LIG1 that engage with mutagenic mismatches inserted by pol beta in base excision repair.
Nat Commun 13 pp.3860 - 3860 2022

Experiment:

X-RAY DIFFRACTION Resolution:3.0Å R work:0.204R free:0.245

NDB ID:

7XLV

PDB ID:

7XLV 

Release:

2022-07-13

Title:

Crystal structure of a NIR-emitting DNA-stabilized Ag16 nanocluster (G7I mutant)

Classification:

DNA

Authors:

Cerretani, C., Liisberg, M.B., Ruck, V., Kondo, J., Vosch, T.

Citation:

The effect of inosine on the spectroscopic properties and crystal structure of a NIR-emitting DNA-stabilized silver nanocluster.
nanoscale advances pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.1Å R work:0.102R free:0.109

NDB ID:

7XLW

PDB ID:

7XLW 

Release:

2022-07-13

Title:

Crystal structure of a NIR-emitting DNA-stabilized Ag16 nanocluster (G7I/G9I mutant)

Classification:

DNA

Authors:

Cerretani, C., Liisberg, M.B., Ruck, V., Kondo, J., Vosch, T.

Citation:

The effect of inosine on the spectroscopic properties and crystal structure of a NIR-emitting DNA-stabilized silver nanocluster.
Nanoscale Adv pp. - 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.89Å R work:0.15R free:0.182

NDB ID:

8A1C

PDB ID:

8A1C 

Release:

2022-07-13

Title:

TraI trans-esterase domain from pKM101 (DNA bound)

Classification:

DNA BINDING PROTEIN

Authors:

Breidenstein, A., ter Beek, J., Berntsson, R.P.-A.

Citation:

Structural and functional characterization of TraI from pKM101 reveals basis for DNA processing
To Be Published pp. - 0

Experiment:

X-RAY DIFFRACTION Resolution:2.1Å R work:0.225R free:0.267

NDB ID:

7M43

PDB ID:

7M43 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, TTP:At Ca2+ Ground State Ternary Complex

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.978Å R work:0.192R free:0.231

NDB ID:

7M44

PDB ID:

7M44 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, TTP:At Mg2+ Reaction State Ternary Complex, 90 sec

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.901Å R work:0.194R free:0.226

NDB ID:

7M45

PDB ID:

7M45 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, TTP:At Mg2+ Reaction State Ternary Complex, 120 sec

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.889Å R work:0.204R free:0.242

NDB ID:

7M46

PDB ID:

7M46 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, TTP:At Mg2+ Product State Ternary Complex, 5 min

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.92Å R work:0.186R free:0.216

NDB ID:

7M47

PDB ID:

7M47 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, TTP:At Mg2+ Product State Ternary Complex, 60 min

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.648Å R work:0.179R free:0.208

NDB ID:

7M48

PDB ID:

7M48 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, TTP:At Mg2+ Product State Ternary Complex, 960 min

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.93Å R work:0.183R free:0.22

NDB ID:

7M49

PDB ID:

7M49 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, TTP:At Mn2+ Reaction State Ternary Complex, 5 min

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.6Å R work:0.187R free:0.216

NDB ID:

7M4A

PDB ID:

7M4A 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, TTP:At Mn2+ Product State Ternary Complex, 20 min

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.868Å R work:0.187R free:0.22

NDB ID:

7M4B

PDB ID:

7M4B 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, TTP:At Mn2+ Product State Ternary Complex, 60 min

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.66Å R work:0.18R free:0.201

NDB ID:

7M4C

PDB ID:

7M4C 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, TTP:At Mn2+ Product State Ternary Complex, 960 min

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.95Å R work:0.181R free:0.214

NDB ID:

7M4D

PDB ID:

7M4D 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, dCTP:At Ca2+ Ground State Ternary Complex

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.817Å R work:0.21R free:0.254

NDB ID:

7M4E

PDB ID:

7M4E 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, dCTP:At Mg2+ Reaction State Ternary Complex, 120 min

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.903Å R work:0.208R free:0.232

NDB ID:

7M4F

PDB ID:

7M4F 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, dCTP:At Mg2+ Product State Ternary Complex, 300 min

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.947Å R work:0.207R free:0.24

NDB ID:

7M4G

PDB ID:

7M4G 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, dCTP:At Mg2+ Product State Ternary Complex, 960 min

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.88Å R work:0.211R free:0.239

NDB ID:

7M4H

PDB ID:

7M4H 

Release:

2022-07-06

Title:

DNA Polymerase Lambda, dCTP:At Mn2+ Reaction State Ternary Complex, 225 min

Classification:

REPLICATION

Authors:

Jamsen, J.A., Shock, D.D., Wilson, S.H.

Citation:

Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.
Nat Commun 13 pp.3193 - 3193 2022

Experiment:

X-RAY DIFFRACTION Resolution:1.923Å R work:0.192R free:0.227